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In Vitro Fertilization – the process of fertilizing a woman’s egg/ ovum with her partner’s sperm outside the body (in a lab). Also known as Test tube baby. IVF has helped millions of couples worldwide overcome fertility challenges and has revolutionized the field of reproductive medicine. Akarsh hospital, Visakhapatnam has acclaimed as the best fertility centre in Visakhapatnam with experts and specialists.
IVF is a type of assisted reproductive technology (ART) that involves fertilizing an egg with sperm outside the body, typically in a laboratory dish or test tube. The process of creating a test tube baby generally involves the following steps:
1. Ovarian Stimulation: The woman undergoing IVF is given fertility drugs to stimulate her ovaries to produce multiple mature eggs instead of the usual one egg per menstrual cycle.
2. Egg Retrieval: Once the eggs have matured, they are retrieved from the woman’s ovaries using a minor surgical procedure known as follicular aspiration. A thin needle is inserted into the ovaries, guided by ultrasound, to collect the eggs.
3. Sperm Collection: The male partner provides a sperm sample through masturbation, which is prepared in the laboratory to isolate healthy sperm.
4. Fertilization: In the laboratory, the retrieved eggs and prepared sperm are combined in a petri dish or test tube, where fertilization takes place. This can be achieved through conventional IVF, where the sperm is added to the dish containing the eggs, or through intracytoplasmic sperm injection (ICSI), where a single sperm is directly injected into each egg.
5. Embryo Culture: After fertilization, the embryos are cultured in a laboratory for a few days to allow them to develop and reach a certain stage of maturity. Embryo Transfer: The most viable and healthy embryos are selected for transfer into the woman’s uterus. This involves inserting a thin catheter through the cervix and into the uterus to carefully place the embryos.
6. Implantation and Pregnancy: If the embryo successfully implants into the uterine lining, pregnancy occurs. A pregnancy test is usually conducted about two weeks after the embryo transfer to confirm whether the IVF procedure was successful.
Testing the couple- factor identification: While evaluating the couple, the team of doctors follow systematic approach like taking proper medical history, physical examination, ovulation assessment, semen analysis as a preliminary test to rule out male infertility, followed by hormonal assessment and other imaging tests. Based on the preliminary diagnosis treatments will be advised.
Counselling: Couple counseling for infertility can be highly beneficial in helping couples navigate the emotional and psychological challenges that often accompany the journey of infertility. Emotional support through communication and advising coping strategies helps the to take decision making. The counselling team from Akarsh fertility helps in the best way to prepare the couple for IVF if they are really willing to go for it.
IUI (Intrauterine insemination): Akarsh Hospitals, known to have higher success rates in performing IUI – artificial insemination. During IUI, prepared and concentrated sperm is directly inserted into the woman’s uterus, bypassing the cervix and bringing the sperm closer to the fallopian tubes where fertilization typically occurs.
IUI is often recommended for couples with unexplained infertility, cervical factor infertility, mild male factor infertility, or for those using donor sperm. It is generally a less invasive and less costly treatment option compared to in vitro fertilization (IVF), but the success rates can vary depending on factors such as the woman’s age, the cause of infertility, and the quality of the sperm used.
IVF/ICSI – Intracytoplasmic insemination: IVF offers hope to individuals and couples facing various infertility factors, including tubal issues, male factor infertility, endometriosis, unexplained infertility, or advanced maternal age. It has revolutionized the field of reproductive medicine and helped couples worldwide in building their families.
ICSI is often performed as part of in vitro fertilization (IVF) treatment and involves the direct injection of a single sperm into an egg to facilitate fertilization. ICSI is commonly used in cases where the male partner has low sperm count, poor sperm motility, abnormal sperm morphology, or other sperm-related issues.
TESA/ PESA: TESA (Testicular Sperm Aspiration) and PESA (Percutaneous Epididymal Sperm Aspiration) are both surgical sperm retrieval techniques used in cases where there is a blockage or absence of sperm in the ejaculate. These procedures are typically performed as part of assisted reproductive technologies (ART) such as in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI) to retrieve sperm directly from the testicles or epididymis. These are sperm retrieval options performed in coordination with IVF. It depends on the case whether to go for TESA or PESA.
Blastocyst culture: Similar to IVF, but a couple of days extra in the laboratory. The prepared embryo stays till day 5 before it enters the woman’s uterus. The advantage of blastocyst culture is that it allows for better selection of the most viable embryos. It also enables the possibility of performing preimplantation genetic testing (PGT) on the embryos, reducing the risk of certain genetic conditions and increasing the chances of success. Blastocyst transfer yields better rates of getting pregnancy.
Cryopreservation: In assisted reproductive technology (ART), cryopreservation is commonly used for the freezing and storage of eggs, sperm, and embryos.
Cryopreservation offers several benefits which includes: Helps couples to preserve their reproductive potential by freezing and storing eggs, embryos, or sperm for future use. This can be particularly useful for individuals undergoing medical treatments that may affect fertility, such as chemotherapy or radiation therapy.
Cryopreservation provides flexibility in the timing of fertility treatments. For example, a woman may choose to freeze her eggs at a younger age when fertility is optimal and use them later when she is ready to start a family. Cryopreserved embryos have shown improved implantation and pregnancy rates compared to fresh embryos..
Akarsh Hospitals, Visakhapatnam has the best embryo preserving facility on par with any top fertility centres in India.
Semen freezing: perm freezing or cryo banking helps in serious health conditions or hazardous situations in future. some men bank their sperm to preserve their fertility. success rates of semen freezing and subsequent fertility treatments can vary depending on various factors, such as the quality of the sperm, the expertise of the laboratory.The best sperm bank with advanced storage technology is with Akarsh hospitals.